Naloxone is an opioid antagonist that reverses overdose.

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Prepare for the CIEMT Medical and Physiology Exam. Study with flashcards and multiple-choice questions that feature explanations. Ace your test!

Multiple Choice

Naloxone is an opioid antagonist that reverses overdose.

Explanation:
Naloxone is the agent that reverses opioid overdose because it binds to mu-opioid receptors with high affinity and acts as a competitive antagonist, displacing opioid molecules and rapidly reversing respiratory depression and decreased consciousness. Other classes listed do not counteract opioid effects: sympathomimetics stimulate adrenergic receptors but don’t block opioid receptor activation; stimulants affect non-opioid pathways to increase alertness or energy; sedative-hypnotics depress the CNS and do not undo opioid receptor activation. Keep in mind that opioids can outlast naloxone, so repeated dosing and monitoring are often needed.

Naloxone is the agent that reverses opioid overdose because it binds to mu-opioid receptors with high affinity and acts as a competitive antagonist, displacing opioid molecules and rapidly reversing respiratory depression and decreased consciousness. Other classes listed do not counteract opioid effects: sympathomimetics stimulate adrenergic receptors but don’t block opioid receptor activation; stimulants affect non-opioid pathways to increase alertness or energy; sedative-hypnotics depress the CNS and do not undo opioid receptor activation. Keep in mind that opioids can outlast naloxone, so repeated dosing and monitoring are often needed.

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