CIEMT Medical and Physiology Practice Exam

Anticholinergic toxidrome. Blocking muscarinic receptors cuts parasympathetic activity, so you get dry skin and mucous membranes (no sweating), hyperthermia from impaired heat dissipation, and mydriasis (dilated pupils). Other signs often include tachycardia and delirium. In contrast, cholinergic toxicity would cause sweating and pinpoint pupils; opioid toxidrome causes miosis and respiratory depression; sympathomimetic toxicity can cause dilated pupils and hyperthermia but usually with sweaty skin, not dry.