Which of the following is NOT a typical feature of cholinergic toxicity?

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Multiple Choice

Which of the following is NOT a typical feature of cholinergic toxicity?

Explanation:
Cholinergic toxicity ramps up parasympathetic activity through excess acetylcholine acting on muscarinic receptors, producing SLUDGE effects: increased secretions, urination, and GI distress are classic features. Pupil response is a key clue: muscarinic stimulation causes constriction of the pupil (miosis) because the sphincter pupillae muscle contracts. Dilated pupils (mydriasis) would come from anticholinergic effects or sympathetic activation, not cholinergic toxicity. So increased secretions, urination, and GI distress fit cholinergic toxicity, while pupil dilation does not.

Cholinergic toxicity ramps up parasympathetic activity through excess acetylcholine acting on muscarinic receptors, producing SLUDGE effects: increased secretions, urination, and GI distress are classic features. Pupil response is a key clue: muscarinic stimulation causes constriction of the pupil (miosis) because the sphincter pupillae muscle contracts. Dilated pupils (mydriasis) would come from anticholinergic effects or sympathetic activation, not cholinergic toxicity. So increased secretions, urination, and GI distress fit cholinergic toxicity, while pupil dilation does not.

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